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KMID : 0355619930190020217
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Journal of Korean Association of Oral and Maxillofacial Surgeons
1993 Volume.19 No. 2 p.217 ~ p.225
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Experimental study on the influence of HCI concentration on the healing process of allogeneic bone graft
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Abstract
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It is generally beleived that the demineralization process does not remove BMP, while the undemineralized bone contains this protein, the bone mineral seems to hinder its action so that the demineralization process make the bone inducing agents
more
available to the host tissue.
The purpose of this study was to evaluate the influence of HC1 concentration o the healing process of 0.4N, 0.5N, and 0.6N HC1 demineralized allogenic bone graft respectively compared with the autografted bone.
@ES The results were as follows:
@EN 1. Inflammatory cell infiltration appeared at 2 weeks and disappeared at 4 weeks in all experimental groups, but especillay severe in 0.4N HC1 demineralized group at 2 weeks.
2. Neovascularization around graft material in 0.5 and 0.6N groups were more than in 0.4N HC1 group.
3. Osteoblastic activity in 0.5 and 0.6N groups were more than in0.4 HC1 group.
4. There were no significant differences of bone resorption among 0.4, 0.5 and k0.6N HC1 groups.
5. New bone formation and mineralization in 0.5 and 0.6N HC1 groups were more than in 0.4N group and were similar to autograft group.
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KEYWORD
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